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CID 5951923
CAS No. 749872-43-3
CID 5951923 ( —— )
Catalog No. M27613 CAS No. 749872-43-3
CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 80 | Get Quote |
|
| 10MG | 102 | Get Quote |
|
| 25MG | 196 | Get Quote |
|
| 50MG | 350 | Get Quote |
|
| 100MG | 524 | Get Quote |
|
| 500MG | 1143 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameCID 5951923
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NoteResearch use only, not for human use.
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Brief DescriptionCID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
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DescriptionCID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.(In Vitro):CID 5951923 (10 μM) inhibits the proliferation of cancer cell lines mainly in highly expressing KLF5 cells. CID 5951923 (0.001, 0.01, 0.1, 1, 10, 100 μM) inhibits proliferation of DLD-1 cells in a dose-dependent manner. CID 5951923 (10 μM) significantly decreases endogenous KLF5 levels in the DLD-1 cells, downregulates EGR1, and increases phosphorylation levels of pEGFFpY1068.
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetDNA/RNA Synthesis
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RecptorROCK2
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Research Area——
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Indication——
Chemical Information
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CAS Number749872-43-3
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Formula Weight382.4
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Molecular FormulaC16H18N2O7S
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Purity>98% (HPLC)
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Solubility——
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SMILESCN([C@H]1CCS(=O)(=O)C1)C(=O)COC(=O)\C=C\c1cccc(c1)[N+]([O-])=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Aicher, Thomas Daniel, et al. INDAZOLYL THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE. US20180093978A1.
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