CID 5951923

CAS No. 749872-43-3

CID 5951923 ( —— )

Catalog No. M27613 CAS No. 749872-43-3

CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 80 Get Quote
10MG 102 Get Quote
25MG 196 Get Quote
50MG 350 Get Quote
100MG 524 Get Quote
500MG 1143 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    CID 5951923
  • Note
    Research use only, not for human use.
  • Brief Description
    CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.
  • Description
    CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.(In Vitro):CID 5951923 (10 μM) inhibits the proliferation of cancer cell lines mainly in highly expressing KLF5 cells. CID 5951923 (0.001, 0.01, 0.1, 1, 10, 100 μM) inhibits proliferation of DLD-1 cells in a dose-dependent manner. CID 5951923 (10 μM) significantly decreases endogenous KLF5 levels in the DLD-1 cells, downregulates EGR1, and increases phosphorylation levels of pEGFFpY1068.
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    DNA/RNA Synthesis
  • Recptor
    ROCK2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    749872-43-3
  • Formula Weight
    382.4
  • Molecular Formula
    C16H18N2O7S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CN([C@H]1CCS(=O)(=O)C1)C(=O)COC(=O)\C=C\c1cccc(c1)[N+]([O-])=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Aicher, Thomas Daniel, et al. INDAZOLYL THIADIAZOLAMINES AND RELATED COMPOUNDS FOR INHIBITION OF RHO-ASSOCIATED PROTEIN KINASE AND THE TREATMENT OF DISEASE. US20180093978A1.
molnova catalog
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